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Mol Clin Oncol

doi: 10.1371/journal.pone.0251677 362 WuL

Research shows that mitochondrial oxidative damage is a critical feature of CRC, with markers such as TBARS and protein carbonyls being significantly elevated in tumor tissues

Furthermore, monothiol class I glutaredoxins can catalyze all essential glutaredoxin- and thioredoxin-dependent protein disulfide reductions in yeast, including, for example, the reduction of RNR and MSR 34